Supervoxel-Based Hierarchical Markov Random Field Framework for Multi-Atlas Segmentation

MICCAI Workshop 2016


Ning Yu1      Hongzhi Wang2      Paul Yushkevich3
1. University of Virginina      2. IBM Almaden Research Center      3. University of Pennsylvania

Abstract


Multi-atlas segmentation serves as an important technique for quantitative analysis of medical images. In many applications, top performing techniques rely on computationally expensive deformable registration to transfer labels from atlas images to the target image. We propose a more computationally efficient label transfer strategy that uses supervoxel matching regularized by Markov random field (MRF), followed by regional voxel-wise joint label fusion and a second MRF. We evaluate this hierarchical MRF framework for multi-label diencephalon segmentation from the MICCAI 2013 SATA Challenge. Our segmentation results are comparable to the top-tier one obtained by deformable registration, but with much lower computational complexity.

Demos

Multi-label diencephalon segmentation

Accuracy and efficiency

Materials




Paper



Slides

Citation

@inproceedings{yu2016supervoxel,
  author = {Yu, Ning and Wang, Hongzhi and Yushkevich, Paul},
  title = {Supervoxel-Based Hierarchical Markov Random Field Framework for Multi-Atlas Segmentation},
  booktitle = {International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) Workshop},
  year = {2016}
}

Acknowledgement


This research is supported by NIH grant R01 EB017255.

Related Work


R. Achanta, A. Shaji, K. Smith, A. Lucchi, P. Fua, S. Süsstrunk. SLIC Superpixels Compared to State-of-the-Art Superpixel Methods. PAMI 2012.
Comment: The SLIC algorithm that is used in our work for supervoxel oversegmentation.
B. Glocker, N. Komodakis, G. Tziritas, N. Navab, N. Paragios. Dense Image Registration through MRFs and Efficient Linear Programming. MIA 2008.
Comment: The Fast-PD algorithm that is used in our work to solve Markov Random Fields.
H. Wang, J. Suh, S. Das, J. Pluta, C. Craige, P. Yushkevich. Multi-Atlas Segmentation with Joint Label Fusion. PAMI 2013.
Comment: A backbone component that is used in our work to account for correlation and redundancy between atlases.
H. Wang, S. Das, J. Suh, M. Altinay, J. Pluta, C. Craige, B. Avants, P. Yushkevich. A Learning-Based Wrapper Method to Correct Systematic Errors in Automatic Image Segmentation: Consistently Improved Performance in Hippocampus, Cortex and Brain Segmentation. Neuroimage 2012.
Comment: A wrapper method that is used in our work to improve the performance of existing segmentation algorithms using training data.
H. Wang, P. Yushkevich. Multi-atlas Segmentation without Registration: A Supervoxel-Based Approach. MICCAI 2013.
Comment: A supervoxel-based multi-atlas segmentation baseline method that performs undesirably without pre-registration.
M. Heinrich, I. Simpson, B. Papiez, M. Brady, J. Schnabel. Deformable Image Registration by Combining Uncertainty Estimates from Supervoxel Belief Propagation. MIA 2016.
Comment: A supervoxel-based image registration method similar in spirit to our work.
D. Zikic, B. Glocker, A. Criminisi. Atlas Encoding by Randomized Forests for Efficient Label Propagation. MICCAI 2013.
Comment: The state-of-the-art baseline method that has similar efficiency but worse segmentation accuracy.